Drug Information

Drug General Information
Drug ID
D0K1UD
Former ID
DIB003639
Drug Name
MMV00/0053
Synonyms
MMV00/0053; PfENR inhibitors, Jacobus; Plasmodium falciparum enoyl acyl carrier protein reductase inhibitors, Jacobus; FAS II inhibitors, Jacobus/MMV; Fatty acid biosynthesis II inhibitors, Jacobus/MMV
Indication Malaria [ICD10:B54] Terminated [551156]
Company
Jacobus Pharmaceutical Co Inc
Structure
Download
2D MOL

3D MOL
Canonical SMILES
c1c(ccc(c1O)Oc1ccc(cc1CNCc1cc2CCOc2cc1)Cl)Cl
Target and Pathway
Target(s) Enoyl-[acyl-carrier-protein] reductase [NADH] Target Info Inhibitor [530687]
References
Ref 551156Annual report of Medicines for Malaria Venture in 2002.
Ref 530687SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. IUBMB Life. 2010 Mar;62(3):204-13.

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