Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0K1UD
|
||||
Former ID |
DIB003639
|
||||
Drug Name |
MMV00/0053
|
||||
Synonyms |
MMV00/0053; PfENR inhibitors, Jacobus; Plasmodium falciparum enoyl acyl carrier protein reductase inhibitors, Jacobus; FAS II inhibitors, Jacobus/MMV; Fatty acid biosynthesis II inhibitors, Jacobus/MMV
|
||||
Indication | Malaria [ICD10:B54] | Terminated | [1] | ||
Company |
Jacobus Pharmaceutical Co Inc
|
||||
Structure |
![]() |
Download2D MOL |
|||
Canonical SMILES |
c1c(ccc(c1O)Oc1ccc(cc1CNCc1cc2CCOc2cc1)Cl)Cl
|
||||
Target and Pathway | |||||
Target(s) | Enoyl-[acyl-carrier-protein] reductase [NADH] | Target Info | Inhibitor | [2] | |
References | |||||
REF 1 | Annual report of Medicines for Malaria Venture in 2002. | ||||
REF 2 | SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase. IUBMB Life. 2010 Mar;62(3):204-13. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.