Drug Information

Drug General Information
Drug ID
D0K3GU
Former ID
DCL000597
Drug Name
PF-3185043
Indication Atherosclerosis [ICD9: 414.0, 440; ICD10:I70] Discontinued in Phase 1 [548432]
Company
Pfizer
Target and Pathway
Target(s) Cholesteryl ester transfer protein Target Info Inhibitor [549974], [551502]
PANTHER Pathway CCKR signaling map ST
Reactome LDL-mediated lipid transport
HDL-mediated lipid transport
WikiPathways Statin Pathway
Lipid digestion, mobilization, and transport
References
Ref 548432Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025537)
Ref 549974Pfizer. Product Development Pipeline. March 31 2009.
Ref 551502Flavonoids as inhibitors of MRP1-like efflux activity in human erythrocytes. A structure-activity relationship study. Oncol Res. 2003;13(11):463-9.

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