TTD | Drug: D0K5UH

Drug General Information
Drug ID	D0K5UH
Former ID	DNC014548
Drug Name	CR-1795
Drug Type	Small molecular drug
Indication	Discovery agent		Terminated	[546448]
Structure		Download 2D MOL 3D MOL
Formula	C27H38N2O4
Canonical SMILES	CCCCCN(CCCCC)C(=O)C(CCCC(=O)O)NC(=O)C1=CC2=CC=CC=C2C=C1
InChI	1S/C27H38N2O4/c1-3-5-9-18-29(19-10-6-4-2)27(33)24(14-11-15-25(30)31)28-26(32)23-17-16-21-12-7-8-13-22(21)20-23/h7-8,12-13,16-17,20,24H,3-6,9-11,14-15,18-19H2,1-2H3,(H,28,32)(H,30,31)/t24-/m1/s1
InChIKey	VHCOMPFCZPOZFX-XMMPIXPASA-N
PubChem Compound ID	44381915
Target and Pathway
Target(s)	Cholecystokinin receptor type A	Target Info	Inhibitor	[551253]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
	Pancreatic secretion
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546448	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008170)
Ref 551253	Biological properties of (R)-4-benzamido-5-oxopentanoic basic derivatives as CCK-antagonists, Bioorg. Med. Chem. Lett. 3(5):861-866 (1993).

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Drug Information