Drug General Information
Drug ID	D0K7XM
Former ID	DNC006212
Drug Name	APLYSAMINE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529632]
Structure		Download 2D MOL 3D MOL
Formula	C15H24Br2N2O
Canonical SMILES	CN(C)CCCOC1=C(C=C(C=C1Br)CCN(C)C)Br
InChI	1S/C15H24Br2N2O/c1-18(2)7-5-9-20-15-13(16)10-12(11-14(15)17)6-8-19(3)4/h10-11H,5-9H2,1-4H3
InChIKey	LWENJEAGCYZOBC-UHFFFAOYSA-N
PubChem Compound ID	362025
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[529632]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529632	J Med Chem. 2008 Sep 11;51(17):5423-30. Epub 2008 Aug 7.The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.
Ref 529632	J Med Chem. 2008 Sep 11;51(17):5423-30. Epub 2008 Aug 7.The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.

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