Drug General Information
Drug ID	D0K8KJ
Former ID	DIB016419
Drug Name	DuP-129
Synonyms	ACAT inhibitors, Du Pont
Indication	Hypercholesterolemia [ICD10:E78]		Terminated	[545519]
Company	Bristol-Myers Squibb Pharma Co
Structure		Download 2D MOL 3D MOL
Canonical SMILES	C1(N=C(N([C@@H]1CC(=O)C1CCCCC1)C)c1ccc(cc1)F)(C(F)(F)F)<br />C(F)(F)F
Target and Pathway
Target(s)	Liver carboxylesterase	Target Info	Inhibitor	[543651]
KEGG Pathway	Drug metabolism - other enzymes
	Metabolic pathways
Pathway Interaction Database	E2F transcription factor network
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Heroin metabolism
	Irinotecan Pathway
	Fluoropyrimidine Activity
	Phase I biotransformations, non P450
References
Ref 545519	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003587)
Ref 543651	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2592).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.