Drug Information

Drug General Information
Drug ID
D0K8VR
Former ID
DIB018307
Drug Name
[3H]HU-243
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542370]
Structure
Download
2D MOL

3D MOL
Formula
C25H40O3
InChI
InChI=1S/C25H40O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h14-15,17,19-20,26-27H,6-13,16H2,1-5H3/t17-,19-,20-/m1/s1/i10T,17T/t10?,17-,19-,20-
InChIKey
MVEVPDCVOXJVBD-AENGYHINSA-N
PubChem Compound ID
3081854
PubChem Substance ID
36412559, 80502517, 111683818, 135229204, 144116053
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Agonist [526736]
Cannabinoid receptor 2 Target Info Agonist [533602]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 542370(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 735).
Ref 526736A novel probe for the cannabinoid receptor. J Med Chem. 1992 May 29;35(11):2065-9.
Ref 533602The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling. FEBS Lett. 1995 Nov 13;375(1-2):143-7.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.