Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0K9DI
|
||||
Former ID |
DIB008594
|
||||
Drug Name |
GSK-356278
|
||||
Synonyms |
PDE4 inhibitor (oral, depression/anxiety), GlaxoSmithKline
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Huntington's disease [ICD9: 294.1, 333.4; ICD10:F02.2, G10] | Phase 1 | [522890] | ||
Company |
Glaxosmithkline
|
||||
Structure |
Download2D MOL |
||||
Formula |
C21H25N7O2S
|
||||
Canonical SMILES |
CCN1C2=NC=C(C(=C2C=N1)NC3CCOCC3)C4=NN=C(O4)CC5=C(N=C(S5<br />)C)C
|
||||
InChI |
1S/C21H25N7O2S/c1-4-28-20-15(11-23-28)19(25-14-5-7-29-8-6-14)16(10-22-20)21-27-26-18(30-21)9-17-12(2)24-13(3)31-17/h10-11,14H,4-9H2,1-3H3,(H,22,25)
|
||||
InChIKey |
AWDJJMXJUOHGLC-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Type IV phosphodiesterase | Target Info | Inhibitor | [532759] | |
CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [532759] | ||
CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [532759] | ||
NetPath Pathway | IL5 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
PathWhiz Pathway | Purine Metabolism | ||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.