Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K9ZU
|
||||
| Former ID |
DIB006843
|
||||
| Drug Name |
CD45RB
|
||||
| Synonyms |
Abeta amyloid agonist (peptide, glioma); Abeta amyloid agonist (peptide, glioma), Lee Moffitt Cancer Center
|
||||
| Indication | Glioma [ICD9: 191; ICD10:C71] | Investigative | [543619] | ||
| Company |
H Lee Moffitt Cancer Center and Research Institute
|
||||
| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
N([C@H](C(=O)O)Cc1ccccc1)C(=O)[C@@H](NC(=O)[C@H](C(C)C)<br />NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(<br />=O)[C@@H](NC(=O)[C@@H](N)C(C)C)Cc1c[nH]cn1)Cc1c[nH]cn1)<br />CCC(=O)N)CCCCN)CC(C)C)Cc1ccccc1
|
||||
| Target and Pathway | |||||
| Target(s) | Amyloid beta A4 protein | Target Info | Agonist | [543619] | |
| KEGG Pathway | Notch signaling pathway | ||||
| Alzheimer's disease | |||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Degradation of the extracellular matrix | |||||
| Regulated proteolysis of p75NTR | |||||
| NRIF signals cell death from the nucleus | |||||
| Activated NOTCH1 Transmits Signal to the Nucleus | |||||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | |||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | |||||
| EPH-ephrin mediated repulsion of cells | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.