Drug General Information
Drug ID
D0L1GI
Former ID
DIB016467
Drug Name
ReS8-T compounds
Synonyms
Alzheimer program (tau-mediated cytotoxicity); Alzheimer program (tau-mediated cytotoxicity), reMYND; Tau detoxifying compounds (Alzheimer's), reMYND; Alzheimer program (tau-mediated cytotoxicity), reMYND/ Roche; ReS10-T compounds (Alzheimer's), reMYND; ReS19-T compounds (Alzheimer's), reMYND; ReS3-T compounds (Alzheimer's), reMYND; ReS8-T compounds (Alzheimer's), reMYND
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Investigative [531616]
Company
ReMYND NV
Target and Pathway
Target(s) Microtubule-associated protein tau Target Info Modulator [531616]
KEGG Pathway MAPK signaling pathway
Alzheimer's disease
NetPath Pathway IL2 Signaling Pathway
EGFR1 Signaling Pathway
Pathway Interaction Database LPA receptor mediated events
Reelin signaling pathway
Reactome Caspase-mediated cleavage of cytoskeletal proteins
WikiPathways Notch Signaling Pathway
IL-2 Signaling Pathway
MAPK Signaling Pathway
Copper homeostasis
Kit receptor signaling pathway
BDNF signaling pathway
Integrated Pancreatic Cancer Pathway
Alzheimers Disease
Regulation of Microtubule Cytoskeleton
Apoptotic execution phase
IL-5 Signaling Pathway
References
Ref 531616Microtubules (tau) as an emerging therapeutic target: NAP (davunetide). Curr Pharm Des. 2011;17(31):3413-7.
Ref 531616Microtubules (tau) as an emerging therapeutic target: NAP (davunetide). Curr Pharm Des. 2011;17(31):3413-7.

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