Drug Information

Drug General Information
Drug ID
D0L1UA
Former ID
DNC009645
Drug Name
N-(4-hydroxybenzyl)icosa-5,8,11,14-tetraenamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529838]
Structure
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2D MOL

3D MOL
Formula
C27H39NO2
Canonical SMILES
CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC1=CC=C(C=C1)O
InChI
1S/C27H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-27(30)28-24-25-20-22-26(29)23-21-25/h6-7,9-10,12-13,15-16,20-23,29H,2-5,8,11,14,17-19,24H2,1H3,(H,28,30)/b7-6-,10-9-,13-12-,16-15-
InChIKey
YSOGPKZWDUJRGP-DOFZRALJSA-N
PubChem Compound ID
10811495
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [529838]
Cannabinoid receptor 1 Target Info Inhibitor [529838]
Cannabinoid receptor 2 Target Info Inhibitor [529838]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signalinghsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Anandamide degradationP05730:Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 529838J Med Chem. 2008 Dec 25;51(24):7800-5.New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide.
Ref 529838J Med Chem. 2008 Dec 25;51(24):7800-5.New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide.

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