Drug Information

Drug General Information
Drug ID
D0L8WT
Former ID
DNC000924
Drug Name
MEN13510
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Investigative [536088]
Structure
Download
2D MOL

3D MOL
Formula
C21H23N5S
Canonical SMILES
CCC(CC)C(C1=CC=C(C=C1)NC2=NC3=CC=CC=C3S2)N4C=NC=N4
InChI
1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25)
InChIKey
SNFYYXUGUBUECJ-UHFFFAOYSA-N
PubChem Compound ID
9799888
PubChem Substance ID
14755739, 24109047, 44835893, 49684199, 53789406, 53789526, 57373367, 76789017, 96026065, 103606247, 104106249, 109614492, 129260859, 134339389, 134340209, 135253080, 135359461, 137128405, 141445542, 163420454, 163620798, 163686123, 163910322, 185972138, 223827847, 227010044, 252459556
Target and Pathway
Target(s) NK-2 receptor Target Info Antagonist [536088]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536088Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor. Eur J Pharmacol. 2005 Jun 1;516(2):104-11.
Ref 536088Pharmacology of an original and selective nonpeptide antagonist ligand for the human tachykinin NK2 receptor. Eur J Pharmacol. 2005 Jun 1;516(2):104-11.

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