Drug General Information
Drug ID
D0LH1A
Former ID
DNC000441
Drug Name
CL 385319
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535252], [535454], [536931], [538146]
Structure
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2D MOL

3D MOL

Formula
C15H18F4N2O
Canonical SMILES
C1CCN(CC1)CCNC(=O)C2=CC(=CC(=C2)F)C(F)(F)F
InChI
1S/C15H18F4N2O/c16-13-9-11(8-12(10-13)15(17,18)19)14(22)20-4-7-21-5-2-1-3-6-21/h8-10H,1-7H2,(H,20,22)
InChIKey
VSXLWIDIFZEXHE-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Hemagglutinin Target Info Inhibitor [535252], [535454], [536931], [538146]
References
Ref 535252An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2393-6.
Ref 535454Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. J Antibiot (Tokyo). 2002 Mar;55(3):239-48.
Ref 536931Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17736-41. Epub 2008 Nov 12.
Ref 538146Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J Virol. 1999 Jan;73(1):140-51.
Ref 535252An approach to the identification of potent inhibitors of influenza virus fusion using parallel synthesis methodology. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2393-6.
Ref 535454Novel stachyflin derivatives from Stachybotrys sp. RF-7260. Fermentation, isolation, structure elucidation and biological activities. J Antibiot (Tokyo). 2002 Mar;55(3):239-48.
Ref 536931Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion. Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):17736-41. Epub 2008 Nov 12.
Ref 538146Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin. J Virol. 1999 Jan;73(1):140-51.

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