Drug Information

Drug General Information
Drug ID
D0M0NT
Former ID
DCL001221
Drug Name
PF-04620110
Drug Type
Small molecular drug
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Terminated [542774], [551489]
Company
Pfizer
Structure
Download
2D MOL

3D MOL
Formula
C21H24N4O4
InChI
InChI=1S/C21H24N4O4/c22-19-18-20(24-12-23-19)29-10-9-25(21(18)28)16-7-5-15(6-8-16)14-3-1-13(2-4-14)11-17(26)27/h5-8,12-14H,1-4,9-11H2,(H,26,27)(H2,22,23,24)/t13-,14-
InChIKey
GEVVQZHMFVFGLN-HDJSIYSDSA-N
PubChem Compound ID
46926360
PubChem Substance ID
99431668, 134439055, 136361828, 140741485, 140741488, 152258414, 160647251, 163417281, 163850533, 186014847, 189053661, 194947306, 223366160, 223626251, 224243112, 227636774, 227636777, 227637413, 238942416, 242059918, 243334996, 247600107, 248170599, 252469077
Target and Pathway
Target(s) Diglyceride acyltransferase Target Info Inhibitor [551489]
BioCyc Pathway Triacylglycerol biosynthesis
KEGG Pathway Glycerolipid metabolism
Retinol metabolism
Metabolic pathways
Fat digestion and absorption
PathWhiz Pathway Retinol Metabolism
Reactome Acyl chain remodeling of DAG and TAG
Triglyceride Biosynthesis
WikiPathways Vitamin A and Carotenoid Metabolism
Statin Pathway
Triacylglyceride Synthesis
Glycerophospholipid biosynthesis
Fatty acid, triacylglycerol, and ketone body metabolism
References
Ref 542774(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7829).
Ref 551489Clinical pipeline report, company report or official report of Pfizer (2011).
Ref 551489Clinical pipeline report, company report or official report of Pfizer (2011).

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