Drug Information

Drug General Information
Drug ID
D0M1FB
Former ID
DIB020566
Drug Name
N-palmitoylethanolamine
Synonyms
palmitoyl-EA; palmitamide MEA
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540483]
Structure
Download
2D MOL
Formula
C18H37NO2
InChI
InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
InChIKey
HXYVTAGFYLMHSO-UHFFFAOYSA-N
PubChem Compound ID
4671
PubChem Substance ID
85235, 6752159, 7850592, 8152869, 11111603, 11113754, 11120210, 11120698, 11121186, 11121519, 11121999, 11147293, 11362588, 11365150, 11367712, 11370447, 11370448, 11373313, 11375874, 14825223, 17405463, 24278619, 26751935, 26751936, 26751937, 29223759, 47290911, 47662029, 47885184, 49661772, 49681174, 50064896, 50104611, 50104612, 50104613, 53778011, 56365485, 56463464, 57309612, 57322388, 77768141, 81054512, 85231178, 90341052, 91053556, 92304274, 92309870, 96025015, 99300784, 99302302
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [543393]
G-protein coupled receptor 55 Target Info Agonist [529051]
KEGG Pathway cAMP signaling pathway
Insulin secretion
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways Incretin Synthesis, Secretion, and InactivationWP1825:GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 540483(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3622).
Ref 529051The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol. 2007 Dec;152(7):1092-101. Epub 2007 Sep 17.
Ref 543393(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 126).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.