Drug General Information
Drug ID	D0M4JK
Former ID	DIB013830
Drug Name	UCB-2892
Synonyms	H3 antagonist (cognitive disorders); UCB-2892; H3 antagonist (cognitive disorders), UCB
Indication	Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3]		Investigative	[543673]
Company	UCB SA
Structure		Download 2D MOL 3D MOL
Canonical SMILES	N1(C(=O)CC[C@H]1CN1CCCC1)c1ccc(cc1)OCCCN1[C@H](CCC1)C
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[543673]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 543673	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).
Ref 543673	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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