Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M5CU
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| Former ID |
DIB011562
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| Drug Name |
YM-337
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| Synonyms |
SMART anti-platelet; YM-387; Anti-gpIIb/IIIa (platelet) MAb, Yamanouchi
|
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| Indication | Angiogenesis disorder [ICD10:I00-I99] | Discontinued in Phase 2 | [545993] | ||
| Company |
Yamanouchi Pharmaceutical Co Ltd
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| CAS Number |
CAS 339086-80-5
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| Target and Pathway | |||||
| Target(s) | Glycoprotein IIb/IIIa receptor | Target Info | Modulator | ||
| Reactome | Platelet degranulation | ||||
| Elastic fibre formation | |||||
| PECAM1 interactions | |||||
| Molecules associated with elastic fibres | |||||
| Integrin cell surface interactions | |||||
| Syndecan interactions | |||||
| ECM proteoglycans | |||||
| Integrin alphaIIb beta3 signaling | |||||
| GRB2:SOS provides linkage to MAPK signaling for Integrins | |||||
| p130Cas linkage to MAPK signaling for integrins | |||||
| VEGFA-VEGFR2 Pathway | |||||
| MAP2K and MAPK activation | |||||
| References | |||||
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