TTD | Drug: D0M7OZ

Drug General Information
Drug ID	D0M7OZ
Former ID	DNC008078
Drug Name	E-GUGGULSTERONE
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529138]
Structure		Download 2D MOL 3D MOL
Formula	C21H28O2
Canonical SMILES	CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
InChI	1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1
InChIKey	WDXRGPWQVHZTQJ-AUKWTSKRSA-N
PubChem Compound ID	6439929
Target and Pathway
Target(s)	Bile acid receptor	Target Info	Inhibitor	[529138]
KEGG Pathway	Bile secretion
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptor
Reactome	Recycling of bile acids and salts
	PPARA activates gene expression
	Endogenous sterols
WikiPathways	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	Farnesoid X Receptor Pathway
	Drug Induction of Bile Acid Pathway
References
Ref 529138	J Nat Prod. 2007 Nov;70(11):1691-5. Epub 2007 Nov 8.Scalarane sesterterpenes from a marine sponge of the genus Spongia and their FXR antagonistic activity.
Ref 529138	J Nat Prod. 2007 Nov;70(11):1691-5. Epub 2007 Nov 8.Scalarane sesterterpenes from a marine sponge of the genus Spongia and their FXR antagonistic activity.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information