Drug Information
Drug General Information | |||||
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Drug ID |
D0M9FQ
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Former ID |
DNCL001869
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Drug Name |
PF-489791
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Drug Type |
Small molecular drug
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Indication | Chronic obstructive pulmonary disease; Raynaud's disease [ICD9: 490-492, 494-496, 443; ICD10:J40-J44, J47, I73.0] | Phase 2 | [548422] | ||
Company |
Pfizer New York, NY
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Structure |
Download2D MOL |
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Formula |
C20H28N8O4S
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Canonical SMILES |
CCN(C)C1=NC2=C(C(=N1)NC3=NC=CC(=C3)C)N(N=C2C(=O)NS(=O)(<br />=O)C)CCOCC
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InChI |
1S/C20H28N8O4S/c1-6-27(4)20-23-15-16(19(29)26-33(5,30)31)25-28(10-11-32-7-2)17(15)18(24-20)22-14-12-13(3)8-9-21-14/h8-9,12H,6-7,10-11H2,1-5H3,(H,26,29)(H,21,22,23,24)
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InChIKey |
ZUHZNKJIJDAJFD-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [551982] | |
KEGG Pathway | Purine metabolism | ||||
cGMP-PKG signaling pathway | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Reactome | cGMP effects | ||||
References |
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