TTD | Drug: D0MJ1L

Drug General Information
Drug ID	D0MJ1L
Former ID	DNC006239
Drug Name	2-morpholino-7-phenyl-4H-chromen-4-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527870]
Structure		Download 2D MOL 3D MOL
Formula	C19H17NO3
Canonical SMILES	C1COCCN1C2=CC(=O)C3=C(O2)C=C(C=C3)C4=CC=CC=C4
InChI	1S/C19H17NO3/c21-17-13-19(20-8-10-22-11-9-20)23-18-12-15(6-7-16(17)18)14-4-2-1-3-5-14/h1-7,12-13H,8-11H2
InChIKey	RWIGISKNQAMRJZ-UHFFFAOYSA-N
PubChem Compound ID	23586694
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[527870]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
Reactome	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
WikiPathways	miR-targeted genes in lymphocytes - TarBase
References
Ref 527870	Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.
Ref 527870	Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity.

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Drug Information