Drug Information

Drug General Information
Drug ID
D0MX5S
Former ID
DAP000616
Drug Name
Enoxaparin
Synonyms
Clexane; Enoxaparine; LMWH; Lovenox; Lovenox HP; Low molecular weight heparin; Low molecular weight heparin sodium; EMT966; EMT 967; EMT966; EMT967; PK10169; Clexane (TN); EMT-966; EMT-967; Heparin, Low Molecular Weight; Lovenox (TN); PK 10,169; PK-10169; PK10,169; Low-Molecular-Weight Heparin; PK-10,169; Heparin, Low-Molecular-Weight; 2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose; 6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
Drug Type
Small molecular drug
Indication Venous thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] Approved [536110], [541893]
Therapeutic Class
Anticoagulants
Company
Sanofi-Aventis
Structure
Download
2D MOL

3D MOL
Formula
C26H42N2O37S5
InChI
InChI=1S/C26H42N2O37S5/c1-4(30)27-7-9(31)13(6(56-23(7)39)3-55-67(43,44)45)58-26-19(65-70(52,53)54)12(34)16(20(62-26)22(37)38)60-24-8(28-66(40,41)42)15(63-68(46,47)48)14(5(2-29)57-24)59-25-18(64-69(49,50)51)11(33)10(32)17(61-25)21(35)36/h5-20,23-26,28-29,31-34,39H,2-3H2,1H3,(H,27,30)(H,35,36)(H,37,38)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)
InChIKey
HTTJABKRGRZYRN-UHFFFAOYSA-N
CAS Number
CAS 9005-49-6
PubChem Compound ID
772
PubChem Substance ID
24439133, 46505194, 46507450, 53787364, 57320468, 76657000, 81065629, 103121404, 104295808, 137267081, 160963753, 178103417, 179235956, 210275694, 210281353, 226852693
ChEBI ID
ChEBI:28304
Target and Pathway
Target(s) Antithrombin-III Target Info Modulator [556264]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
Pathway Interaction Database Glypican 1 network
Reactome Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
WikiPathways Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 536110Pharmacologic profile of certoparin. Expert Opin Investig Drugs. 1999 Mar;8(3):315-27.
Ref 541893(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6811).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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