Drug General Information |
Drug ID |
D0N0OY
|
Former ID |
DNC005220
|
Drug Name |
2-(4-Hydroxy-phenyl)-benzooxazol-5-ol
|
Drug Type |
Small molecular drug
|
Indication |
Discovery agent
|
Investigative |
[1]
|
Structure |
|
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2D MOL
3D MOL
|
Formula |
C13H9NO3
|
Canonical SMILES |
C1=CC(=O)C=CC1=C2NC3=C(O2)C=CC(=C3)O
|
InChI |
1S/C13H9NO3/c15-9-3-1-8(2-4-9)13-14-11-7-10(16)5-6-12(11)17-13/h1-7,14,16H
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InChIKey |
YTIGNSMQLOIUBU-UHFFFAOYSA-N
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PubChem Compound ID |
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Target and Pathway |
Target(s) |
Estrogen receptor beta |
Target Info |
Inhibitor |
[1]
|
Estrogen receptor |
Target Info |
Inhibitor |
[1]
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KEGG Pathway
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Estrogen signaling pathway
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Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
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Prolactin signaling pathway
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Thyroid hormone signaling pathway
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Endocrine and other factor-regulated calcium reabsorption
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Proteoglycans in cancer
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NetPath Pathway
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FSH Signaling Pathway
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EGFR1 Signaling Pathway
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RANKL Signaling Pathway
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Pathway Interaction Database
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Plasma membrane estrogen receptor signaling
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Validated nuclear estrogen receptor beta network
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Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
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Signaling events mediated by HDAC Class II
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LKB1 signaling events
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Regulation of Telomerase
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ATF-2 transcription factor network
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AP-1 transcription factor network
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FOXM1 transcription factor network
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Validated nuclear estrogen receptor alpha network
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Signaling mediated by p38-alpha and p38-beta
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FOXA1 transcription factor network
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Reactome
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Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
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Nuclear Receptor transcription pathway
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WikiPathways
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SIDS Susceptibility Pathways
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Ovarian Infertility Genes
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Integrated Pancreatic Cancer Pathway
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Nuclear ReceptorsWP712:Estrogen signaling pathway
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Nuclear Receptors Meta-Pathway
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Estrogen Receptor Pathway
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Signaling by ERBB4
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JAK/STAT
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Leptin signaling pathway
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miR-targeted genes in muscle cell - TarBase
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Integrated Breast Cancer Pathway
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Nuclear Receptors
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References |
REF 1 | J Med Chem. 2004 Oct 7;47(21):5021-40.Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. |