Drug General Information
Drug ID
D0N0RN
Former ID
DNCL003486
Drug Name
Marizomib
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 1 [550092]
Company
Nereus Pharmaceuticals
Structure
Download
2D MOL

3D MOL

Formula
C15H20ClNO4
Canonical SMILES
CC12C(C(=O)NC1(C(=O)O2)C(C3CCCC=C3)O)CCCl
InChI
1S/C15H20ClNO4/c1-14-10(7-8-16)12(19)17-15(14,13(20)21-14)11(18)9-5-3-2-4-6-9/h3,5,9-11,18H,2,4,6-8H2,1H3,(H,17,19)/t9-,10+,11+,14+,15+/m1/s1
InChIKey
NGWSFRIPKNWYAO-SHTIJGAHSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Proteasome Target Info Inhibitor [531339]
References
Ref 550092Clinical pipeline report, company report or official report of Triphase Accelerator .
Ref 531339Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Curr Cancer Drug Targets. 2011 Mar;11(3):254-84.

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