Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N1WU
|
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| Former ID |
DAP000778
|
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| Drug Name |
Etodolac
|
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| Drug Type |
Small molecular drug
|
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| Therapeutic Class |
Analgesics
|
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| Company |
Meda Pharmaceuticals
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| Structure |
|
Download2D MOL |
|||
| Formula |
C17H21NO3
|
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| InChIKey |
NNYBQONXHNTVIJ-UHFFFAOYSA-N
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| CAS Number |
CAS 41340-25-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9204, 143623, 224459, 855612, 5268437, 7847381, 7979205, 8149693, 8152106, 10321309, 11335322, 11360561, 11364138, 11366700, 11369262, 11372457, 11373819, 11377424, 11461533, 11466259, 11467379, 11485110, 11485958, 11489203, 11491244, 11492225, 11495058, 12012673, 14824710, 17405042, 24278407, 26612147, 26680024, 26747213, 26747214, 29222445, 46505184, 47885271, 47959585, 47959586, 48034967, 48110316, 48184861, 48259079, 48334348, 48413770, 49698757, 49857374, 50105240, 50105241
|
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| SuperDrug ATC ID |
M01AB08
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| SuperDrug CAS ID |
cas=041340254
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| Target and Pathway | |||||
| Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [535206], [536446] | |
| KEGG Pathway | Arachidonic acid metabolism | ||||
| Metabolic pathways | |||||
| NF-kappa B signaling pathway | |||||
| VEGF signaling pathway | |||||
| TNF signaling pathway | |||||
| Retrograde endocannabinoid signaling | |||||
| Serotonergic synapse | |||||
| Ovarian steroidogenesis | |||||
| Oxytocin signaling pathway | |||||
| Regulation of lipolysis in adipocytes | |||||
| Leishmaniasis | |||||
| Pathways in cancer | |||||
| Chemical carcinogenesis | |||||
| MicroRNAs in cancer | |||||
| Small cell lung cancer | |||||
| PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
| References | |||||
| Ref 538288 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074819. | ||||
| Ref 542196 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7185). | ||||
| Ref 535206 | Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines. Int J Urol. 2001 Jul;8(7):S35-9. | ||||
| Ref 536446 | Membranous nephropathy associated with the relatively selective cyclooxygenase-2 inhibitor, etodolac, in a patient with early rheumatoid arthritis. Intern Med. 2007;46(13):1055-8. Epub 2007 Jul 2. | ||||
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