Drug Information

Drug General Information
Drug ID
D0N3YN
Former ID
DIB020607
Drug Name
ONO-3080573
Synonyms
ON3
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533273]
Structure
Download
2D MOL
Formula
C31H34O7
InChI
InChI=1S/C31H34O7/c1-19-26(35-2)16-22(17-27(19)36-3)29(32)28(38-25-14-20-6-4-5-7-21(20)15-25)18-37-24-10-8-23(9-11-24)31(12-13-31)30(33)34/h4-11,16-17,25,28-29,32H,12-15,18H2,1-3H3,(H,33,34)/t28-,29+/m0/s1
InChIKey
FVESDCZDESZGHA-URLMMPGGSA-N
PubChem Compound ID
91799238
PubChem Substance ID
251963609, 252166789
Target and Pathway
Target(s) Lysophosphatidic acid receptor Edg-2 Target Info Antagonist [533273]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
PI3K-Akt signaling pathway
Gap junction
Pathways in cancer
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database LPA receptor mediated events
Reactome G alpha (q) signalling events
G alpha (i) signalling events
Lysosphingolipid and LPA receptors
WikiPathways Myometrial Relaxation and Contraction Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 533273Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43.
Ref 533273Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43.

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