Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N6YV
|
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| Former ID |
DIB012782
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| Drug Name |
Cenestin
|
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| Synonyms |
Synthetic conjugated estrogens-A, Barr; Synthetic conjugated estrogens-A, Duramed
|
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| Drug Type |
Small molecular drug
|
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| Indication | Menopause symptoms [ICD10:N95.0] | Approved | [551871] | ||
| Company |
Duramed Pharmaceuticals Inc
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| Structure |
|
Download2D MOL |
|||
| Formula |
C18H19NaO5S
|
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| Canonical SMILES |
[Na+].O=S(=O)(Oc1cc2c([C@@H]3[C@H]([C@H]4[C@](CC3)(C(=O<br />)CC4)C)CC2)cc1)[O-].[Na+].O=S(=O)(Oc1cc2c([C@@H]3C(=CC2<br />)[C@H]2[C@](CC3)(C(=O)CC2)C)cc1)[O-]
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| CAS Number |
CAS 12126-59-9
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Estrogen receptor | Target Info | Agonist | [526290], [551871] | |
| Pathway Interaction Database | Regulation of nuclear SMAD2/3 signaling | ||||
| Signaling events mediated by HDAC Class II | |||||
| Plasma membrane estrogen receptor signaling | |||||
| LKB1 signaling events | |||||
| Regulation of Telomerase | |||||
| ATF-2 transcription factor network | |||||
| AP-1 transcription factor network | |||||
| FOXM1 transcription factor network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Signaling mediated by p38-alpha and p38-beta | |||||
| FOXA1 transcription factor network | |||||
| References | |||||
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