Drug General Information
Drug ID
D0N7WW
Former ID
DNCL001716
Drug Name
RVX-208
Drug Type
Small molecular drug
Indication Alzheimer disease; Atherosclerosis [ICD9: 331, 414.0, 440; ICD10:G30, I70] Phase 1/2 [522457], [542052]
Company
Resverlogix
Structure
Download
2D MOL
Formula
C20H22N2O5
InChI
InChI=1S/C20H22N2O5/c1-11-7-13(8-12(2)18(11)27-6-5-23)19-21-15-9-14(25-3)10-16(26-4)17(15)20(24)22-19/h7-10,23H,5-6H2,1-4H3,(H,21,22,24)
InChIKey
NETXMUIMUZJUTB-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Bromodomain-containing protein 4 Target Info Modulator
WikiPathways Chemical Compounds to monitor Proteins
References
Ref 522457ClinicalTrials.gov (NCT00768274) Safety, Pharmacokinetic Study of RVX000222 in Healthy Subjects and Subjects With Low HDL Cholesterol. U.S. National Institutes of Health.
Ref 542052(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7034).

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