Drug General Information
Drug ID
D0NH0U
Former ID
DIB003113
Drug Name
HYG-440
Synonyms
HYG-410; HYG-420; HYG-430; Androgen receptor antagonists (topical, dermatological disorder), hygeia
Indication Dermatological disease [ICD10:L00-L99] Investigative [552008]
Company
Yale University
Target and Pathway
Target(s) Androgen receptor Target Info Antagonist [552008]
KEGG Pathway Oocyte meiosis
Pathways in cancer
Prostate cancer
NetPath Pathway EGFR1 Signaling Pathway
AndrogenReceptor Signaling Pathway
FSH Signaling Pathway
Pathway Interaction Database Regulation of nuclear SMAD2/3 signaling
Coregulation of Androgen receptor activity
Regulation of Androgen receptor activity
Nongenotropic Androgen signaling
Regulation of nuclear beta catenin signaling and target gene transcription
FOXA1 transcription factor network
Notch-mediated HES/HEY network
Reactome Nuclear Receptor transcription pathway
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
WikiPathways SIDS Susceptibility Pathways
Integrated Pancreatic Cancer Pathway
Prostate Cancer
Integrated Breast Cancer Pathway
Nuclear Receptors
Androgen receptor signaling pathway
References
Ref 552008Clinical pipeline report, company report or official report of Hygeia Therapeutics.
Ref 552008Clinical pipeline report, company report or official report of Hygeia Therapeutics.

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