Drug Information

Drug General Information
Drug ID
D0NI0C
Former ID
DAP000642
Drug Name
Vidarabine
Synonyms
ADN; Adenocard; Adenocor; Adenoscan; Adenosin; Adenosine; Adensoine; Araadenosine; Arabinosyladenine; Armes; Boniton; Myocol; Nucleocardyl; Pallacor; Polyadenosine; Polyriboadenosine; RAB; Sandesin; Spongoadenosine; VIRDARABINE; Vidarabin; Vidarabina; Vidarabinum; Xylosyladenine; Adenine arabinoside; Adenine nucleoside; Adenine riboside; Adenine xyloside; Adenosin [German]; Adenosine arabinose; Ara A; Arabinoside adenine; Arabinosyl adenine; Vidarabina [DCIT]; Vidarabine anhydrous; Vira ATM; Xylosyl A; A 9251; SR 96225; ARA-A NSC 247519; Ade-Rib; Adenocard (TN); Adenocard, Adenosine; Adenoscan (TN); Adenosine [USAN:BAN]; Alpha-Ara A; Ara-A; Arabinosyl-adenine; Arasena-A; Armes (TN); Beta-Adenosine; Beta-Ara A; MEDR-640; SR-96225; SUN-Y4001; USAF CB-10; Vidarabine (JAN); Vira-A; Adenine-D-ribose; Adenosine (JAN/USP); Adenosine-8-14C; Beta-D-Adenosine; Vira-A, Vidarabine; ADENOSINE, U.S.P.; (+)-Cyclaradine; 9-Arabinosyladenine
Drug Type
Small molecular drug
Indication Herpes simplex virus infection [ICD9: 54; ICD10:B00] Approved [468037], [538596]
Therapeutic Class
Antiviral Agents
Structure
Download
2D MOL

3D MOL
Formula
C10H13N5O4
InChI
InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1
InChIKey
OIRDTQYFTABQOQ-UHTZMRCNSA-N
CAS Number
CAS 24356-66-9
PubChem Compound ID
21704
PubChem Substance ID
602757, 1493762, 7890208, 7980879, 8149583, 8165985, 11335366, 11360605, 11364830, 11367392, 11369954, 11371600, 11374363, 11378122, 11461577, 11485227, 11489152, 11490396, 11492597, 11495708, 14799159, 14848243, 24891019, 26611977, 26679886, 26697127, 26740884, 29289080, 46506630, 47193870, 47207955, 47217036, 47365446, 47515571, 47515572, 47959993, 48334764, 49865027, 50123560, 53788311, 56324720, 57264435, 57304786, 57330956, 76747708, 91011419, 92124449, 92307566, 92309102, 99301279
ChEBI ID
ChEBI:45327
SuperDrug ATC ID
J05AB03; S01AD06
SuperDrug CAS ID
cas=005536174
Target and Pathway
Target(s) Adenosine A2b receptor Target Info Modulator [556264]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Alcoholism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
Reactome Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 468037(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4806).
Ref 538596FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 050486.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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