Drug Information

Drug General Information
Drug ID
D0NJ3V
Former ID
DAP000959
Drug Name
Papaverine
Synonyms
Alapav; Cardiospan; Cardoverina; Ceraspan; Cerebid; Cerespan; Delapav; Dilaves; Dispamil; Drapavel; Durapav; Dynovas; Forpavin; Genabid; Mesotina; Myobid; Pameion; Pamelon; Panergon; Papacon; Papalease; Papanerin; Papanerine; Papaverin; Papaverina; Papaversan; Pavabid; Pavacap; Pavacels; Pavacen; Pavacot; Pavagen; Pavarine; Pavatest; Pavatine; Pavatym; Paverolan; Paveron; Pavnell; Robaxapap; Vasal; Chlorhydrate de papaverine; PAP H; Papavarine chlorhydrate; Papaverina [Italian]; Papaverine Hcl; Papaverine [BAN]; Papaverine chlorohydrate; Papaverine monohydrochloride; Papaverinium chloride; Pavabid Hp; Qua bid; EV1; RS 47; TNP00305; Alapav (TN); Albatran (TN); Artegodan (TN); Cardiospan (TN); Cardioverina (TN); Cepaverin (TN); Cerebid (TN); Cerespan (TN); Delapav (TN); Dicertan (TN); Dilaves (TN); Dispamil (TN); Drapavel (TN); Durapav (TN); Dynovas (TN); Forpaven (TN); Houde (TN); Mesotina (TN); Myobid (TN); Opdensit (TN); Optenyl (TN); Pameion (TN); Pamelon (TN); Panergon (TN); Papacon (TN); Papalease (TN); Papanerin-hcl; Papaverine (BAN); Papaversan (TN); Pavabid (TN); Pavacap (TN); Pavacen (TN); Pavadel (TN); Pavadyl (TN); Pavagen (TN); Pavakey (TN); Pavased (TN); Pavatest (TN); Paverina (TN); Paverolan (TN); Paveron (TN); Pavnell (TN); Qua bid (TN); Ro-Papav; Therapav (TN); Vasal (TN); Vaso-Pav; Vasospan (TN); Papanerin-hcl (TN); Papaverin-Hamelin (TN); Papital T.R.; Paptial T.R.; Ro-Papav (TN); S-M-R; Spasmo-Nit (TN); Vaso-Pav (TN); Pap-Kaps-150 (TN); Papital T.R. (TN); Paptial T.R. (TN); Isoquinoline,6,7-dimethoxy-1-veratryl-(8CI); Isoquinoline, 6,7-dimethoxy-1-veratryl-(8Cl); 1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline; 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-isoquinoline; 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline; 1-[(3,4-Dimethoxyphenyl)methyl]6,7-dimethoxyisoquinoline; 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline; 1-{[3,4-bis(methyloxy)phenyl]methyl}-6,7-bis(methyloxy)isoquinoline; 4-[(6,7-Dimethoxyisoquinolyl)methyl]-1,2-dimethoxybenzene; 6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)isoquinoline; 6,7-Dimethoxy-1-veratrylisoquinoline
Drug Type
Small molecular drug
Indication Spasm [ICD9: 728.85; ICD10:R25.2] Approved [550750]
Therapeutic Class
Vasodilator Agents
Structure
Download
2D MOL

3D MOL
Formula
C20H21NO4
Canonical SMILES
COC1=C(C=C(C=C1)CC2=NC=CC3=CC(=C(C=C32)OC)OC)OC
InChI
1S/C20H21NO4/c1-22-17-6-5-13(10-18(17)23-2)9-16-15-12-20(25-4)19(24-3)11-14(15)7-8-21-16/h5-8,10-12H,9H2,1-4H3
InChIKey
XQYZDYMELSJDRZ-UHFFFAOYSA-N
CAS Number
CAS 61-25-6
PubChem Compound ID
4680
PubChem Substance ID
8763, 424468, 589990, 596069, 893182, 3727082, 6757319, 8152875, 10528414, 10589551, 11111623, 11111624, 11111625, 11335496, 11360735, 11362885, 11365447, 11368009, 11371753, 11374053, 11376171, 11407575, 11461707, 11466611, 11467731, 11484751, 11486381, 11488794, 11490353, 11492282, 11493885, 11537650, 14875623, 29223768, 46508003, 46515081, 47440156, 47440157, 47515227, 47515228, 47662194, 47662195, 47736379, 47810656, 47959646, 48110367, 48184908, 48259142, 48334400, 48416377
SuperDrug ATC ID
A03AD01; G04BE02
SuperDrug CAS ID
cas=000058742
Target and Pathway
Target(s) CGMP-specific 3',5'-cyclic phosphodiesterase Target Info Inhibitor [535712]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Reactome cGMP effects
References
Ref 550750Drug information of Papaverine, 2008. eduDrugs.
Ref 535712Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. Asian J Androl. 2003 Mar;5(1):15-8.

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