Drug Information

Drug General Information
Drug ID
D0NZ1U
Former ID
DAP001402
Drug Name
Mitomycin C
Synonyms
Ametycin; Ametycine; MMC; Mitamycin; Mitomicina; Mitomycin; Mitomycine; Mitomycins; Mitomycinum; Mitozytrex; Muamycin; Mutamycin; Mytomycin; Mytozytrex; Mitocin C; Mitomycin C from Streptomyces caespitosus; Mitomycinum C; Mitomycyna C; Mitomycyna C [Polish]; Mit-C; Mito-C; Mitocin-C; Mitomicina [INN-Spanish]; Mitomycin (TN); Mitomycin C (JP15); Mitomycin C, Streptomyces caespitosus; Mitomycin-C; Mitomycine [INN-French]; Mitomycinum [INN-Latin]; Muamycin (TN); Mitomycin (USP/INN); Mitomycin [USAN:INN:BAN]; Mitomycin C, Streptomyces caespitosus, Carrier-Free; 7-Amino-9alpha-methoxymitosane
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Approved [536361]
Therapeutic Class
Anticancer Agents
Structure
Download
2D MOL

3D MOL
Formula
C15H18N4O5
Canonical SMILES
CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
InChI
1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
InChIKey
NWIBSHFKIJFRCO-WUDYKRTCSA-N
CAS Number
CAS 50-07-7
PubChem Compound ID
5746
PubChem Substance ID
8906, 87663, 613813, 7847275, 8144500, 8153525, 11120094, 11120582, 11121070, 11121809, 11122289, 11147177, 11363021, 11365583, 11368145, 11371173, 11371174, 11373746, 11376307, 14899962, 14924490, 15249200, 24896554, 24896555, 24896917, 26759169, 26759192, 29224783, 46508353, 47440503, 47440504, 47589205, 48414068, 48416286, 48423722, 49854359, 50064401, 50111457, 53787087, 56310827, 56311910, 56312869, 56312950, 56313687, 56313798, 56313799, 56314173, 56314310, 57260126, 57322926
ChEBI ID
ChEBI:27504
SuperDrug ATC ID
L01DC03
SuperDrug CAS ID
cas=000050077
Target and Pathway
Target(s) DNA Target Info [534930]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 534930Structural studies of atom-specific anticancer drugs acting on DNA. Pharmacol Ther. 1999 Sep;83(3):181-215.

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