Drug General Information
Drug ID	D0O1HL
Former ID	DIB011930
Drug Name	SC-49483
Drug Type	Small molecular drug
Indication	Acquired immune deficiency syndrome [ICD9: 42; ICD10:B20]		Phase 2	[521416]
Company	GD Searle & Co
Structure		Download 2D MOL 3D MOL
Formula	C26H45NO8
Canonical SMILES	[C@@H]1([C@@H]([C@H](CN([C@@H]1COC(=O)CCC)CCCC)OC(=O)CC<br />C)OC(=O)CCC)OC(=O)CCC
CAS Number	CAS 131262-82-3
PubChem Compound ID	60807
Target and Pathway
Target(s)	Maltase-glucoamylase, intestinal	Target Info	Inhibitor	[534275]
KEGG Pathway	Galactose metabolism
	Starch and sucrose metabolism
	Metabolic pathways
	Carbohydrate digestion and absorption
PathWhiz Pathway	Starch and Sucrose Metabolism
WikiPathways	Metabolism of carbohydrates
References
Ref 521416	ClinicalTrials.gov (NCT00000791) A Phase II Double-Blind Study of Two Doses of SC-49483 in Combination With Zidovudine (ZDV) Versus ZDV. U.S. National Institutes of Health.
Ref 534275	Pathology of perbutylated-N-butyl-1-deoxynojiromycin (an alpha-glucosidase-1 inhibitor) in Sprague-Dawley rats. Toxicol Pathol. 1996 Sep-Oct;24(5):531-8.

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