Drug Information

Drug General Information
Drug ID
D0O3QI
Former ID
DNC012030
Drug Name
Benzo[1,3]dioxol-5-ylmethyl-quinazolin-4-yl-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533856]
Structure
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2D MOL

3D MOL
Formula
C16H13N3O2
Canonical SMILES
C1OC2=C(O1)C=C(C=C2)CNC3=NC=NC4=CC=CC=C43
InChI
1S/C16H13N3O2/c1-2-4-13-12(3-1)16(19-9-18-13)17-8-11-5-6-14-15(7-11)21-10-20-14/h1-7,9H,8,10H2,(H,17,18,19)
InChIKey
MLVNLAHRZDXSAM-UHFFFAOYSA-N
PubChem Compound ID
10356247
Target and Pathway
Target(s) CGMP-specific 3',5'-cyclic phosphodiesterase Target Info Inhibitor [533856]
KEGG Pathway Purine metabolism
cGMP-PKG signaling pathway
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Reactome cGMP effects
References
Ref 533856J Med Chem. 1994 Jun 24;37(13):2106-11.Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-substitution of quinazoline derivatives for potent and selective inhibitory activity.
Ref 533856J Med Chem. 1994 Jun 24;37(13):2106-11.Cyclic GMP phosphodiesterase inhibitors. 2. Requirement of 6-substitution of quinazoline derivatives for potent and selective inhibitory activity.

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