Drug Information

Drug General Information
Drug ID
D0O3SA
Former ID
DIB009128
Drug Name
ATL-801
Synonyms
BWA-1433; Adenosine A2b receptor antagonists (coronary artery occlusion), Pennsylvania State University;Adenosine A2b receptor antagonists (diabetes), Pennsylvania State University
Drug Type
Small molecular drug
Indication Non-insulin dependent diabetes [ICD10:E11.9] Investigative [467715]
Company
Pennsylvania State University
Structure
Download
2D MOL

3D MOL
Formula
C20H22N4O4
InChI
InChI=1S/C20H22N4O4/c1-3-11-23-18-16(19(27)24(12-4-2)20(23)28)21-17(22-18)14-8-5-13(6-9-14)7-10-15(25)26/h5-10H,3-4,11-12H2,1-2H3,(H,21,22)(H,25,26)/b10-7+
InChIKey
UGCOFEOEBHUEHA-JXMROGBWSA-N
PubChem Compound ID
6439089
PubChem Substance ID
11968206, 14755975, 14829448, 43032041, 47359837, 47509996, 47657045, 47657046, 50024731, 57368409, 78972861, 103180999, 103944987, 114557750, 135084913, 135140020, 135650042, 136351136, 179293818, 224910672, 232265503, 232265506
Target and Pathway
Target(s) Adenosine A2b receptor Target Info Antagonist [543534]
KEGG Pathway Rap1 signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Alcoholism
NetPath Pathway TGF_beta_Receptor Signaling Pathway
TCR Signaling Pathway
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
Reactome Adenosine P1 receptors
G alpha (s) signalling events
Surfactant metabolism
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 467715(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 443).
Ref 543534(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 20).

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