| Drug General Information |
| Drug ID |
D0O4QB
|
| Former ID |
DNC010687
|
| Drug Name |
EUGENOL
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C10H12O2
|
| InChI |
InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3
|
| InChIKey |
RRAFCDWBNXTKKO-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
12636, 74509, 125977, 588506, 597975, 866329, 3133265, 5268443, 8139909, 8146418, 8149344, 8152109, 10538901, 11335867, 11361106, 11371571, 11375463, 11462078, 11484964, 11489080, 11490462, 11493597, 11528359, 11537592, 15321782, 17389879, 24862128, 24869788, 24894609, 24901114, 24901115, 26611744, 26679332, 26747361, 26747362, 26753011, 29204126, 37904874, 47206065, 47365196, 47515328, 47959753, 48413772, 48421969, 48423424, 48425142, 50105594, 50105595, 50800114, 53787078
|
| Target and Pathway |
| Target(s) |
mRNA of androgen receptor |
Target Info |
Inhibitor |
[2]
|
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KEGG Pathway
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Oocyte meiosis
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Pathways in cancer
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Prostate cancer
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NetPath Pathway
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EGFR1 Signaling Pathway
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AndrogenReceptor Signaling Pathway
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FSH Signaling Pathway
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Pathway Interaction Database
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Regulation of nuclear SMAD2/3 signaling
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Coregulation of Androgen receptor activity
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Regulation of Androgen receptor activity
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Nongenotropic Androgen signaling
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Regulation of nuclear beta catenin signaling and target gene transcription
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FOXA1 transcription factor network
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Notch-mediated HES/HEY network
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Reactome
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Nuclear Receptor transcription pathway
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Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
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WikiPathways
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SIDS Susceptibility Pathways
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Integrated Pancreatic Cancer Pathway
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Prostate Cancer
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Integrated Breast Cancer Pathway
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Nuclear Receptors
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Androgen receptor signaling pathway
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| References |
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2425). |
|---|
| REF 2 | Bioorg Med Chem Lett. 2010 Apr 1;20(7):2111-4. Epub 2010 Feb 21.Effect of essential oils, such as raspberry ketone and its derivatives, on antiandrogenic activity based on in vitro reporter gene assay. |
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