TTD | Drug: D0O4SH

Drug General Information
Drug ID	D0O4SH
Former ID	DIB014139
Drug Name	SAR-156597
Synonyms	IL-4/IL-13-targeting bispecific mAb (idiopathic pulmonary fibrosis), sanofi-aventis
Drug Type	Antibody
Indication	Pulmonary fibrosis [ICD9: 515, 516.3; ICD10:J84.1]		Phase 2	[549242]
Company	Sanofi
Target and Pathway
Target(s)	Interleukin-4 receptor alpha chain	Target Info		[543460]
KEGG Pathway	Cytokine-cytokine receptor interaction
	PI3K-Akt signaling pathway
	Jak-STAT signaling pathway
	Hematopoietic cell lineage
	Inflammatory bowel disease (IBD)
NetPath Pathway	IL2 Signaling Pathway
	IL4 Signaling Pathway
	EGFR1 Signaling Pathway
PANTHER Pathway	Interleukin signaling pathway
Pathway Interaction Database	p73 transcription factor network
Pathway Interaction Database	IL4-mediated signaling events
WikiPathways	Inflammatory Response Pathway
WikiPathways	IL-4 Signaling Pathway
References
Ref 549242	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034106)
Ref 543460	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1697).

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Drug Information