Drug General Information
Drug ID	D0O5YZ
Former ID	DIB013577
Drug Name	Mepindolol
Synonyms	Mepindolol Bio Tsd; PH-851; Mepindolol, Pharmed/SB
Drug Type	Small molecular drug
Indication	Angina pectoris [ICD9: 413; ICD10:I20]		Approved	[551871]
Company	Pharmed Dr Liedtke GmbH
Structure		Download 2D MOL 3D MOL
Formula	C30H46N4O8S
Canonical SMILES	c12c([nH]c(c1)C)cccc2OCC(CNC(C)C)O
CAS Number	CAS 23694-81-7
PubChem Compound ID	6917859
Target and Pathway
Target(s)	Beta-3 adrenergic receptor	Target Info	Modulator	[533373], [544004], [551871]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Neuroactive ligand-receptor interaction
	Endocytosis
	Salivary secretion
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Beta3 adrenergic receptor signaling pathway
Reactome	Adrenoceptors
	G alpha (s) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 533373	Pharmacological studies on the intrinsic sympathomimetic activity of the beta-adrenoceptor antagonist mepindolol. Arzneimittelforschung. 1986 May;36(5):811-3.
Ref 544004	Pindolol--a beta-adrenoceptor blocking drug with partial agonist activity: clinical pharmacological considerations.. Br J Clin Pharmacol. 1982; 13(Suppl 2): 187S-192S.
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.