Drug General Information
Drug ID
D0O7IZ
Former ID
DIB001369
Drug Name
Anti-MIF antibodies
Synonyms
Antimacrophage inhibitory factor, Baxter; Anti-MIF antibodies (inflammation); Anti-MIF antibodies (inflammation), Baxter; Anti-MIF technology, Cytokine/IDEC; Anti-inflammatories, Cytokine/IDEC; Anti-macrophage inhibitory factor, Cytokine/IDEC
Indication Autoimmune diabetes [ICD10:E08-E13] Phase 4 [523659]
Company
Baxter healthcare
Target and Pathway
Target(s) Macrophage migration inhibitory factor Target Info Inhibitor [544220]
KEGG Pathway Tyrosine metabolism
Phenylalanine metabolism
PathWhiz Pathway Tyrosine Metabolism
WikiPathways Spinal Cord Injury
Adipogenesis
References
Ref 523659ClinicalTrials.gov (NCT01452997) Evaluation of Anti-inflammatories in the Reduction of Bite Reactions. U.S. National Institutes of Health.
Ref 544220Neutralization of Macrophage Migration Inhibitory Factor (MIF) by Fully Human Antibodies Correlates with Their Specificity for the beta-Sheet Structure of MIF. J Biol Chem. 2012 March 2; 287(10): 7446-7455.

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