Drug General Information
Drug ID	D0O9EM
Former ID	DIB010020
Drug Name	Eptapirone
Synonyms	F-11440
Drug Type	Small molecular drug
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Discontinued in Phase 1	[546879]
Company	Pierre Fabre SA
Structure		Download 2D MOL 3D MOL
Formula	C16H23N7O2
Canonical SMILES	n1(c(=O)n(ncc1=O)CCCCN1CCN(c2ncccn2)CC1)C
CAS Number	CAS 179756-58-2
PubChem Compound ID	208928
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Agonist	[527844]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546879	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010848)
Ref 527844	The use of sleep measures to compare a new 5HT1A agonist with buspirone in humans. J Psychopharmacol. 2005 Nov;19(6):609-13.

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