Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0OH1O
|
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| Former ID |
DIB016031
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| Drug Name |
VULM-1457
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| Synonyms |
Acyl CoA cholesterol acyltransferase inhibitor (dyslipidemia/atherosclerosis), Univerzity Komenskeho v Bratislave
|
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| Indication | Atherosclerosis [ICD9: 414.0, 440; ICD10:I70] | Investigative | [1] | ||
| Company |
Univerzity Komenskeho v Bratislave
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
c1(NC(=O)Nc2ccc(Sc3ccc([N+](=O)[O-])cc3)cc2)c(C(C)C)ccc<br />c1C(C)C
|
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| Target and Pathway | |||||
| Target(s) | Liver carboxylesterase | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Drug metabolism - other enzymes | ||||
| Metabolic pathways | |||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| WikiPathways | NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | |||||
| Heroin metabolism | |||||
| Irinotecan Pathway | |||||
| Fluoropyrimidine Activity | |||||
| Phase I biotransformations, non P450 | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2592). | ||||
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