Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0OK8M
|
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| Former ID |
DIB012752
|
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| Drug Name |
TEI-6522
|
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| Indication | Arteriosclerosis [ICD9: 440; ICD10:I70] | Terminated | [1] | ||
| Company |
Teijin Ltd
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
c1(c2c(C(=O)CCO2)ccc1OC)NC(=O)C(CCCCCCCCCC)(C)C
|
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| CAS Number |
CAS 141772-64-7
|
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| Target and Pathway | |||||
| Target(s) | Liver carboxylesterase | Target Info | Modulator | [2] | |
| KEGG Pathway | Drug metabolism - other enzymes | ||||
| Metabolic pathways | |||||
| Pathway Interaction Database | E2F transcription factor network | ||||
| WikiPathways | NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | |||||
| Heroin metabolism | |||||
| Irinotecan Pathway | |||||
| Fluoropyrimidine Activity | |||||
| Phase I biotransformations, non P450 | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004501) | ||||
| REF 2 | Potent inhibitors of acyl-CoA:cholesterol acyltransferase. Structure-activity relationships of novel N-(4-oxochroman-8-yl)amides. J Med Chem. 1995 Aug 4;38(16):3174-86. | ||||
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