Drug General Information
Drug ID
D0OS7K
Former ID
DNCL002501
Drug Name
EGEN-001
Indication Fallopian tube cancer; Peritoneal cancer; Ovarian cancer [ICD9: 140-229, 183.2, 221.0, 183; ICD10:C57, D28, C56] Phase 2 [523029]
Company
EGEN
Target and Pathway
Target(s) Interleukin-12 ligand Target Info Modulator [550403]
KEGG Pathway Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Jak-STAT signaling pathway
Type I diabetes mellitus
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Amoebiasis
Tuberculosis
Measles
Influenza A
Herpes simplex infection
Inflammatory bowel disease (IBD)
Allograft rejection
WikiPathways Toll-like receptor signaling pathway
Aryl Hydrocarbon Receptor Pathway
Allograft Rejection
Regulation of toll-like receptor signaling pathway
References
Ref 523029ClinicalTrials.gov (NCT01118052) EGEN-001 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer. U.S. National Institutes ofHealth.
Ref 550403National Cancer Institute Drug Dictionary (drug id 454593).

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