Drug General Information
Drug ID	D0OT1S
Former ID	DIB006982
Drug Name	CP-4200
Synonyms	Lipidated azacitidine (cancer, Lipid Vector), Clavis Pharma; 5-azacytidine-5'-elaidate
Indication	Cancer [ICD9: 140-229; ICD10:C00-C96]		Investigative	[543657]
Company	Clavis Pharma AS
Structure		Download 2D MOL 3D MOL
Canonical SMILES	n1(c(=O)nc(nc1)N)[C@@H]1O[C@@H]([C@H]([C@H]1O)O)COC(=O)<br />CCCCCCC/C=C/CCCCCCCC
Target and Pathway
Target(s)	DNMT1	Target Info	Inhibitor	[543657]
KEGG Pathway	Cysteine and methionine metabolism
	Metabolic pathways
	MicroRNAs in cancer
Pathway Interaction Database	Regulation of retinoblastoma protein
PathWhiz Pathway	Methionine Metabolism
Reactome	PRC2 methylates histones and DNA
	NoRC negatively regulates rRNA expression
	DNA methylation
WikiPathways	Trans-sulfuration and one carbon metabolism
	Retinoblastoma (RB) in Cancer
	One Carbon Metabolism
	Trans-sulfuration pathway
References
Ref 543657	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2605).
Ref 543657	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2605).

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