TTD | Drug: D0OY8Y

Drug General Information
Drug ID	D0OY8Y
Former ID	DIB021113
Drug Name	UCM 549
Synonyms	UCM-549; UCM549
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542724]
Structure		Download 2D MOL
Formula	C19H21NO2
InChI	InChI=1S/C19H21NO2/c1-13(21)20-12-17-10-15-6-4-3-5-14(15)9-16-7-8-18(22-2)11-19(16)17/h3-8,11,17H,9-10,12H2,1-2H3,(H,20,21)
InChIKey	PQZZGTZTKGECDT-UHFFFAOYSA-N
PubChem Compound ID	11185529
PubChem Substance ID	16266406, 23374839, 42265224, 77436768, 103454488, 103923936, 223366105, 246989492
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Antagonist	[529075]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 542724	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7772).
Ref 529075	Synthesis, enantiomeric resolution, and structure-activity relationship study of a series of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene MT2 receptor antagonists. ChemMedChem. 2007 Dec;2(12):1741-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information