Drug General Information
Drug ID	D0P2UM
Former ID	DNC009711
Drug Name	2-(ethoxycarbonyl)-1H-indole-5-carboxylic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530151]
Structure		Download 2D MOL 3D MOL
Formula	C12H11NO4
Canonical SMILES	CCOC(=O)C1=CC2=C(N1)C=CC(=C2)C(=O)O
InChI	1S/C12H11NO4/c1-2-17-12(16)10-6-8-5-7(11(14)15)3-4-9(8)13-10/h3-6,13H,2H2,1H3,(H,14,15)
InChIKey	CAVYPAYXEMVXMS-UHFFFAOYSA-N
PubChem Compound ID	18071365
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Inhibitor	[530151]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 530151	J Med Chem. 2009 Jul 9;52(13):3855-68.5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity.
Ref 530151	J Med Chem. 2009 Jul 9;52(13):3855-68.5-hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity.

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