Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0P3XO
|
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| Former ID |
DIB018106
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| Drug Name |
(S)-4CPG
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| Synonyms |
(S)-4-carboxyphenylglycine
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [538895] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C9H9NO4
|
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| InChI |
InChI=1S/C9H9NO4/c10-7(9(13)14)5-1-3-6(4-2-5)8(11)12/h1-4,7H,10H2,(H,11,12)(H,13,14)/t7-/m0/s1
|
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| InChIKey |
VTMJKPGFERYGJF-ZETCQYMHSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Metabotropicglutamate receptor 1 | Target Info | Antagonist | [526599] | |
| Metabotropic glutamate receptor 5 | Target Info | Antagonist | [525911] | ||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Metabotropic glutamate receptor group III pathway | |||||
| Metabotropic glutamate receptor group I pathway | |||||
| Endogenous cannabinoid signalingP00027:Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Endogenous cannabinoid signaling | |||||
| References | |||||
| Ref 525911 | Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. J Neurochem. 2000 Dec;75(6):2590-601. | ||||
| Ref 526599 | [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. Mol Pharmacol. 2003 May;63(5):1082-93. | ||||
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