TTD | Drug: D0P4GP

Drug General Information
Drug ID	D0P4GP
Former ID	DIB020768
Drug Name	PSB1114
Synonyms	PSB-1114; PSB 1114
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541195]
Structure		Download 2D MOL
Formula	C10H15F2N2O13P3S
InChI	InChI=1S/C10H15F2N2O13P3S/c11-10(12,28(18,19)20)29(21,22)27-30(23,24)25-3-4-6(15)7(16)8(26-4)14-2-1-5(31)13-9(14)17/h1-2,4,6-8,15-16H,3H2,(H,21,22)(H,23,24)(H,13,17,31)(H2,18,19,20)/t4-,6-,7-,8-/m1/s1
InChIKey	DFGBPSGNGNHNQM-XVFCMESISA-N
PubChem Compound ID	52952605
PubChem Substance ID	123104246, 131280487, 131344837, 178102525
Target and Pathway
Target(s)	P2Y purinoceptor 2	Target Info	Agonist	[531402]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL5 Signaling Pathway
Reactome	G alpha (q) signalling events
	P2Y receptors
	Surfactant metabolism
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541195	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5902).
Ref 531402	Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y2, P2Y4, and P2Y6 receptors. J Med Chem. 2011 Apr 28;54(8):2878-90.

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Drug Information