Drug Information

Drug General Information
Drug ID
D0Q0GY
Former ID
DIB013666
Drug Name
IW-1221
Synonyms
CRTH2 inhibitor (asthma), Ironwood
Indication Asthma [ICD10:J45] Investigative [543776]
Company
Ironwood Pharmaceuticals Inc
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Inhibitor [543776]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 543776(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).
Ref 543776(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).

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