Drug Information
Drug General Information | |||||
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Drug ID |
D0Q1HF
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Former ID |
DIB018793
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Drug Name |
NCGC00167772-01
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Synonyms |
NCGC00167772-01; 10-DEBC
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
Download2D MOL |
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Formula |
C20H25ClN2O
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InChI |
InChI=1S/C20H25ClN2O/c1-3-22(4-2)13-7-8-14-23-17-9-5-6-10-19(17)24-20-12-11-16(21)15-18(20)23/h5-6,9-12,15H,3-4,7-8,13-14H2,1-2H3
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InChIKey |
GYBXAGDWMCJZJK-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | Proto-oncogene pim-1 | Target Info | Inhibitor | [2] | |
KEGG Pathway | Jak-STAT signaling pathway | ||||
MicroRNAs in cancer | |||||
Acute myeloid leukemia | |||||
NetPath Pathway | IL9 Signaling Pathway | ||||
IL5 Signaling Pathway | |||||
IL2 Signaling Pathway | |||||
TGF_beta_Receptor Signaling Pathway | |||||
TCR Signaling Pathway | |||||
Pathway Interaction Database | GMCSF-mediated signaling events | ||||
Validated targets of C-MYC transcriptional activation | |||||
Role of Calcineurin-dependent NFAT signaling in lymphocytes | |||||
IL5-mediated signaling events | |||||
IL3-mediated signaling events | |||||
C-MYB transcription factor network | |||||
WikiPathways | Ectoderm Differentiation | ||||
Hematopoietic Stem Cell Differentiation | |||||
References | |||||
REF 1 | Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35. Epub 2005 Jul 11. | ||||
REF 2 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2158). | ||||
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