Drug General Information
Drug ID
D0Q1HK
Former ID
DNC011816
Drug Name
2-Dipropylamino-1,2,3,4-tetrahydro-anthracen-9-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551246]
Structure
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2D MOL

3D MOL

Formula
C20H27NO
Canonical SMILES
CCCN(CCC)C1CCC2=CC3=CC=CC=C3C(=C2C1)O
InChI
1S/C20H27NO/c1-3-11-21(12-4-2)17-10-9-16-13-15-7-5-6-8-18(15)20(22)19(16)14-17/h5-8,13,17,22H,3-4,9-12,14H2,1-2H3
InChIKey
TXKDLYBWCJNMHU-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [551246]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 551246Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile, Bioorg. Med. Chem. Lett. 3(10):2035-2038 (1993).
Ref 551246Synthesis of new derivatives of 8-OH-DPAT: Influence of substitution on the aromatic ring on the pharmacological profile, Bioorg. Med. Chem. Lett. 3(10):2035-2038 (1993).

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