Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Q6EN
|
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| Former ID |
DIB009347
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| Drug Name |
AHR-16303B
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Terminated | [1] | ||
| Company |
A H Robins Co Inc
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| Structure |
|
Download2D MOL |
|||
| Formula |
C33H37F2NO7
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| Canonical SMILES |
C(c1ccc(cc1)F)(c1ccc(cc1)F)(C1CCN(CC1)CCCOc1ccc(C(=O)C(<br />C)C)cc1)O.C(=O)(C(=O)O)O
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| CAS Number |
CAS 117023-62-8
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Calcium channel | Target Info | Modulator | [1] | |
| 5-HT 2 receptor | Target Info | Modulator | [1] | ||
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | AHR-16303B, a novel antagonist of 5-HT2 receptors and voltage-sensitive calcium channels. J Cardiovasc Pharmacol. 1991 Jan;17(1):41-53. | ||||
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